Supplementation with Menaquinone-7 (as MenaQ7®) Slows the

The first results from the VitaK-CAC Trial, “Menaquinone-7 Slows Down Progression of Coronary Artery Calcification: A Randomized, Placebo-Controlled Trial,” were presented at the 34th European Meeting on Hypertension and Cardiovascular Protection, organized by the European Society of Hypertension (ESH), held in Milan in May 23–26, 2025.

What is VitaK-CAC?

The study, “Menaquinone-7 supplementation to reduce vascular calcification in patients with coronary artery disease (VitaK-CAC trial),” was designed to explore the protective effect of vitamin K2 as MK-7 (menaquinone-7 as MenaQ7^®) supplementation on slowing down the progression of coronary artery calcification (CAC), lending further understanding to the mechanism by which K2 inhibits calcification to cardiovascular vessels.

Primary Outcomes Presented

The first findings of this randomized, double-blind, placebo-controlled clinical trial were presented at the conference in Milan, showing that a two-year period of supplementation with MK-7 can slow down the progression of CAC in patients with mild to moderate coronary artery disease, irrespective of blood pressure status.

More to Come

The VitaK-CAC Trial was initiated on the heels of the groundbreaking 3-year MenaQ7^® cardiovascular study’s publication. The full results are expected to be published this year and presented at additional prestigious conferences and congresses.

Ingredients mentioned

MenaQ7®

Active ingredients

Vitamin K2: MenaQ7^® is the optimal bioavailable 99.8% all-trans vitamin K2 as MK-7, produced in the only European plant manufacturing K2 by natural fermentation under the highest quality standards and sustainability measures.

Mobility & Joint
Wellness & Immune
Reproduction & Women’s

Bone
Cardiovascular
Menopause

MenaQ7® Palm-Free MCT Oil

Active ingredients

Vitamin K2 : for oil-based, sustainable, and palm-free finished product formulations, MenaQ7^® Palm-Free MCT Oil combines natural fermentation's purest all-trans vitamin K2, the clinically proven health benefits of MenaQ7^®, and a 100% organic coconut oil carrier. Produced in Europe in Gnosis GMP certified plant.

Mobility & Joint
Wellness & Immune
Reproduction & Women’s

Bone
Cardiovascular
Menopause

MenaQ7® Matrix

Active ingredients

Vitamin K2 : The clinically proven health benefits of MenaQ7^® delivered via an award-winning Vitamin K2 Matrix protective technology. Formulate even under the harshest conditions of supplement & food processing with MenaQ7^® Matrix, the natural choice for stable and protected Vitamin K2, without coating, nor additives.

Mobility & Joint
Wellness & Immune
Reproduction & Women’s

Bone
Cardiovascular
Menopause

Supplementation with Menaquinone-7 (as MenaQ7^®) Slows the Progression of Coronary Artery Calcification

What is VitaK-CAC?

Primary Outcomes Presented

More to Come