Quatreflora™

Throughout their lives, 75% of women will encounter intimate infections. Whether it is due to hormonal changes, stress, sex life, contraception, or antibiotics, the reasons for these infections are so numerous and part of a woman's life that recurrences are not rare. Those factors may lead to a disruption of the vaginal microflora fragile system and thus impact their quality of life and confidence and can be responsible for persisting fatigue.  

Gnosis has answered this challenge, helping women enhance their confidence and nurture their health.  

Enter Quatreflora™: a new probiotic approach for women's intimate health concerns. Produced from a patented strain of  Saccharomyces cerevisiae  CNCM I-3856, it is a probiotic yeast that balances and optimizes vaginal flora and protects against bacterial and yeast vaginosis. Several published pre-clinical and clinical studies demonstrate the efficacy and beneficial effects of Quatreflora™. 

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Quatreflora S.cerevisiae CNCMI-3856
  • Product category
  • Biotics
  • Market segments
    • Reproduction & Women’s
  • Health benefits
    • VaginalCareVaginal Care
  • Allergens and
    certificates
  • Gluten-free
  • Halal
  • Kosher
  • Lactose-free
  • Non GMO
  • Vegetarian-vegan iconVegetarian and Vegan

Quatreflora™: flexibility and versatility for the best quality finished products

Quatreflora™ is manufactured under Good Manufacturing Practices (cGMP) and is a certified Active Pharmaceutical Ingredient (API) for use in over-the-counter and prescription products.

Key Health Benefits of Quatreflora™

  • Vaginal epithelium protection
  • Reduction of inflammation induced by virulence factors in candidiasis infection
  • Reduction of vaginal load of C.albians
  • Inhibition of recurrence of vaginal infections
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Clinically Proven to Clear C.albicans

Oral supplementation with Quatreflora™ over a two-month period decreased vaginal load of Cerevisiae albicans by over half, and decreased the risk of recurrence.

A Natural Breakthrough for Yeast Infections

A 2018 study explored the potential mechanisms of Quatreflora™, particularly examining the probiotic capacity to modulate both fungus and host-related factors. According to the researchers, the data suggest that the beneficial effect exerted by this S. cerevisiae-based probiotic is the result of its interference with the expression of fungus virulence factors coupled with the modulation of the inflammatory response of the host. Read more about this study here.

Inhibits Gardnerella Vaginalis Infection

Gardnerella vaginalis represents a core pathogen for bacterial vaginosis. To that end, researchers explored and demonstrated for the first time that Quatreflora™, a S. cerevisiae-based product, shows an inhibitory effect on G.vaginalis. The study offered the first building blocks of evidence of Quatreflora™’s probability as a proactive strategy for better vaginal health, and that evidence continues to grow. Read more about this discovery here. 

Fostering Consumer Compliance

After oral administration, Quatreflora™ has been shown to migrate from intestinal flora to vaginal flora where it may exert its beneficial effects. This oral administration has a double advantage since Quatreflora™ can exert an early antipathogenic action in the intestines, thus inhibiting the recurrence of vaginal infections. And because Quatreflora™ can be taken orally this also means better compliance, which is often the pet peeve when women start a proactive health strategy. 

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