What is Salidroside?

Salidroside is a compound naturally found in the roots of Rhodiola rosea, an adaptogenic herb used in traditional medicine.  


Salidroside has been studied for its potential antioxidant, anti-inflammatory, and neuroprotective properties. It is believed to help the body adapt to stress and may offer benefits for cognitive function, cardiovascular health, and overall well-being. While present in low concentrations in the plant, Gnosis' innovative fermentation process allows it to obtain 98% pure and consistent Salidroside for nutraceutical and sports nutrition purposes. 

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What Is Salidroside?
What Role Does Salidroside Play in Human Health?

Salidroside is a bioactive compound primarily extracted from the roots of the Rhodiola rosea plant, a traditional adaptogenic herb. As an adaptogen, salidroside is believed to help the body adapt to various forms of stress by modulating the activity of the hypothalamic-pituitary-adrenal (HPA) axis. This can help mitigate the negative effects of stress, such as increased inflammation and oxidative stress.  
 

Salidroside has also demonstrated potential neuroprotective properties, suggesting it may help protect the brain from the damaging effects of oxidative stress and inflammation, which are linked to neurodegenerative conditions. Additionally, research indicates Salidroside may offer cardiovascular benefits by improving endothelial function, reducing blood pressure, and lowering the risk of arterial stiffening.

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While the exact mechanisms are not fully understood, the available evidence suggests Salidroside plays a significant role in supporting overall human health and well-being, particularly in stress management, cognitive function, and cardiovascular health. 

OUR SALIDROSIDE RANGE

Why Is Salidroside So Important?

Salidroside, is garnering significant attention due to its multifaceted health benefits. As an adaptogen, salidroside plays a crucial role in helping the body adapt to various forms of stress by modulating the hypothalamic-pituitary-adrenal (HPA) axis, the body’s main stress response system.  

Beyond its adaptogenic properties, Salidroside also exhibits potent antioxidant and anti-inflammatory activities, which can help protect cells and tissues from harm. This makes Salidroside particularly valuable for supporting overall cellular and organ health, including the brain.  

Furthermore, Salidroside has demonstrated promising cardiovascular effects, including improving endothelial function, reducing blood pressure, and inhibiting the development of arterial stiffness. These actions can contribute to a reduced risk of cardiovascular damage, making Salidroside a valuable supplement for supporting heart health. 

Given its multifaceted benefits, Salidroside has become an increasingly sought-after compound in the health and wellness industry, particularly for its potential applications in stress management, cognitive function, and overall well-being.

How Does Salidroside Work?

Salidroside, a bioactive compound derived from the Rhodiola rosea plant, is believed to exert its beneficial effects through a variety of mechanisms. As an adaptogen, Salidroside is thought to help the body adapt to various forms of stress by modulating the activity of the hypothalamic-pituitary-adrenal (HPA) axis, the body’s main stress response system.  

By regulating the HPA axis, Salidroside may help mitigate the negative consequences of chronic stress, such as increased inflammation and oxidative stress. This anti-inflammatory and antioxidant activity of Salidroside has been observed in numerous studies, suggesting it may help protect cells and tissues from damage.  

Furthermore, Salidroside has been shown to improve endothelial function, reduce blood pressure, and inhibit the development of arterial stiffening, potentially contributing to its cardioprotective effects. These actions may help lower the risk of cardiovascular compromised cardiovascular health and related complications.  

While the exact mechanisms are not fully elucidated, the multifaceted actions of Salidroside, including its adaptogenic, antioxidant, anti-inflammatory, and neuroprotective properties, suggest it may play a significant role in supporting overall health and well-being. 

Is Salidroside the Same as LANDKIND® Pure Salidroside?

Salidroside and LANDKIND® Pure Salidroside are not exactly the same. Salidroside is the bioactive compound found in the Rhodiola rosea plant, while LANDKIND® Pure Salidroside refers to Gnosis’ active ingredient of just pure Salidroside.  

LANDKIND® Pure Salidroside is produced through an innovative and sustainable fermentation process, offering a consistent, high-quality source of pure Salidroside.  

Furthermore, LANDKIND® Pure Salidroside is supported by a clinical study. Its purpose was to evaluate the short-term effects of Salidroside made by fermentation supplementation on exercise performance and mood state. Positive results have been found, demonstrating that LANDKIND® Pure Salidroside may:  

  • Enhance oxygen uptake during exercise
  • Mitigate mood disturbances, particularly in areas of fatigue-related inertia and friendliness  
  • Help inhibit performance deficits due to accumulated fatigue.
     

More than 720 scientific papers, including 22 reviews, support the use of Salidroside as a stand-alone ingredient. The above-mentioned clinical study is the first of its kind and confirms its interest as an important bioactive of Rhodiola in sports nutrition. That’s why Salidroside is the go-to ingredient in sports nutrition.

HEALTHY HINTS: BASICS OF SALIDROSIDE

  • SOURCE: SALIDROSIDE IS PRIMARILY EXTRACTED FROM THE ROOTS OF THE RHODIOLA ROSEA PLANT, ALSO KNOWN AS GOLDEN ROOT OR ARCTIC ROOT. 

  • ADAPTOGENIC PROPERTIES: AS AN ADAPTOGEN, SALIDROSIDE HELPS THE BODY ADAPT TO VARIOUS FORMS OF PHYSICAL, MENTAL, AND EMOTIONAL STRESS.  

  • ANTI-INFLAMMATORY AND ANTIOXIDANT EFFECTS: SALIDROSIDE HAS DEMONSTRATED POTENT ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITIES, WHICH MAY PROTECT CELLS AND TISSUES FROM DAMAGE. 

  • NEUROPROTECTIVE POTENTIAL: RESEARCH SUGGESTS SALIDROSIDE MAY HELP PROTECT THE BRAIN BY REDUCING OXIDATIVE STRESS, NEUROINFLAMMATION, AND CELL DEATH.  
  • CARDIOVASCULAR BENEFITS: SALIDROSIDE MAY IMPROVE ENDOTHELIAL FUNCTION, LOWER BLOOD PRESSURE, AND INHIBIT THE DEVELOPMENT OF ARTERIAL STIFFENING, POTENTIALLY REDUCING THE RISK OF COMPROMISED CARDIOVASCULAR HEALTH. 

  • STANDARDIZED EXTRACTS: RHODIOLA ROSEA CONTAINS RELATIVELY LOW CONCENTRATIONS OF SALIDROSIDE, SO STANDARDIZED EXTRACTS OR GNOSIS’ FERMENTATION PROCESS ALLOWS TO OBTAIN HIGHER AND MORE CONSISTENT DOSES.  

  • VERSATILE APPLICATIONS: SALIDROSIDE SUPPLEMENTS ARE COMMONLY USED FOR STRESS MANAGEMENT, COGNITIVE ENHANCEMENT, AND OVERALL HEALTH AND WELL-BEING. 

Salidroside Benefits

As an adaptogen, Salidroside helps the body adapt to various forms of stress by modulating the HPA axis, mitigating the negative effects of chronic stress. Salidroside’s potent antioxidant and anti-inflammatory properties may protect cells and tissues from damage. Furthermore, Salidroside has demonstrated cardiovascular support by improving endothelial function, lowering blood pressure, and inhibiting arterial stiffening, potentially reducing the risk of compromised heart health. These versatile applications make Salidroside a valuable supplement for overall health and well-being. 

Mitigate Stress

Salidroside helps regulate the body’s stress response system by modulating the hypothalamic-pituitary-adrenal (HPA) axis. This can effectively mitigate the detrimental effects of chronic stress, including increased inflammation and oxidative stress, thereby supporting overall health and well-being. 

A meditative person in nature
A person measuring heart rate

Cardiovascular Health

Emerging research indicates that Salidroside may also offer cardiovascular benefits. The compound has been shown to improve endothelial function, reduce blood pressure, and inhibit the development of arterial stiffening. These actions can contribute to a reduced risk of cardiovascular compromised cardiovascular health, making Salidroside a promising natural supplement for supporting heart health. 

Antioxidant & Anti-inflammatory

Salidroside also exhibits potent antioxidant and anti-inflammatory properties. These actions help protect cells and tissues from the damaging effects of oxidative stress and inflammation, which are implicated in various health conditions. This makes Salidroside a valuable compound for supporting overall cellular and organ health. 

Jogger acknowledging shoulder tension

HOW CAN SALIDROSIDE BE OBTAINED?

Wild Rhodiola Rosea in Arctic Mountain

Salidroside, the bioactive compound found in Rhodiola rosea, can be obtained through various methods. The primary natural source is the extraction of Salidroside from the roots of the Rhodiola rosea plant using techniques like solvent extraction or supercritical fluid extraction. To increase the concentration and ensure consistent quality, manufacturers often produce standardized Rhodiola extracts rich in Salidroside. Additionally, Salidroside can be synthetically produced in a laboratory setting, allowing for the creation of pure, pharmaceutical-grade Salidroside. Advances in biotechnology have also enabled the production of Salidroside through microbial fermentation using genetically engineered strains of bacteria or yeast. Regardless of the source, the goal is to obtain a high-quality, consistent, and concentrated form of Salidroside for use in supplements, functional foods, and other applications.