Vitamin K2 and its Forms
Vitamin K2, specifically menaquinone-7 (MK-7), is crucial for bone and cardiovascular health. MK-7 activates osteocalcin, which helps bind calcium into bones, thus enhancing bone mineral density.
Additionally, MK-7 supports heart health by activating matrix Gla protein (MGP), preventing calcium deposits in arteries, which reduces cardiovascular disease risk and improves blood flow.
Sources of Vitamin K2
Vitamin K2 can be sourced through natural fermentation or chemical synthesis. Natural fermentation produces MK-7, a highly effective form of vitamin K2. Dietary sources of vitamin K2 are limited, making it difficult to achieve an adequate intake of K2 in food alone.
Therefore, supplementation is often recommended to meet daily needs and address vitamin K2 deficiency.
Natural Fermentation vs. Synthesis
Vitamin K2 obtained through natural fermentation uses microorganisms like Bacillus subtilis, providing a superior form of MK-7. In contrast, synthetic vitamin K2 is created through chemical processes and often contains a higher proportion of the less effective cis isomer. This distinction is crucial for those seeking the full benefits of K2 in food.
Isomeric Purity of MK-7
MK-7 exists as trans and cis isomers, with the trans form being the bioactive version essential for health benefits. High-quality MK-7 supplements from natural fermentation usually have over 99% isomeric purity, indicating a predominance of the trans form. Synthetic MK-7 may have a higher percentage of cis isomers, making natural fermentation a preferable method for obtaining effective vitamin K2.