Fertility is a key topic for men and women. The main concern is about infertility. Almost 15% of the reproductive-aged couples worldwide are affected by fertility problems.
Infertility is considered as a disease of the male or female reproductive system by the World Health Organization. It is defined by the failure to achieve a pregnancy after 12 months or more regular unprotected sexual intercourse.
Between 48 million couples and 186 million individuals have infertility globally. It concerns around one in six people in the world. Female infertility alone represents 35% of all infertility cases. Male infertility contributes to 20-50% of infertility cases.
Male infertility can have different origins such as:
- Dysfunction in the ejection of the semen
- Absence or low levels of sperm
- Abnormal shape and movement of the sperm
Selenium is a trace element found in low concentration in food. Selenium is involved in male fertility. Thanks to its action, Selenium is eligible on European claim on fertility. Selenium contributes to normal spermatogenesis.
In addition, selenium offers other benefits on male fertility. Selenium may influence the biosynthesis and secretion of testosterone. This hormone is one of the most important in male fertility. Selenium may be also needed to maintain testicular morphology.
Selenium actions on fertility are mostly impacted by two selenoproteins:
- Glutathione Peroxidase A also called GPx4
- Selenoprotein P
Glutathione Peroxidase 4 is important for fertility. This protein allows the DNA protection of sperm from oxidative stress during initial phases of spermatogenesis. GPx4 is also able to ensure the integrity and motility to sperm. It is also may be involved in the stabilization of condensed chromatin during sperm maturation.
Selenoprotein P may be also considered as an oxidant defense agent. It is also an essential component of the selenium delivery pathway for developing spermatogenic cells.
Lynside® Forte Se+ is an organically bound selenium yeast produced by Gnosis by Lesaffre. This selenium yeast is full of selenomethionine, the highest bioavailable source of selenium, two times higher than inorganic selenium salts.
Another ingredient from Gnosis by Lesaffre is interesting for male fertility: Quatrefolic®.
Quatrefolic®, as folate, is essential in spermatogenesis. Indeed, low folate is associated to:
- Poor sperm DNA stability and damage
- Low sperm count
- Poor sperm motility and morphology
To support women fertility, one of the best options is Quatrefolic®. Quatrefolic®, the innov’Active folate, is the biological active form of folate everyone can used without any enzymatic convertion step. Indeed, Quatrefolic® is indispensable for follicular and embryonic development.
The polymorphism of MTHFR gene have been related to higher homocysteine levels. This high homocysteine level is associated to:
- Difficulties getting pregnant
- Increased risk of miscarriage
Quatrefolic® can bypass this polymorphism. Thanks to this ability, Quatrefolic® has the capacity to decrease the homocysteine level. This decrease may improve the change to get pregnant.
A supplementation is associated to a higher rate of successful pregnancies.
In addition to its properties on men fertility, selenium is also an important mineral for women fertility. As antioxidant, selenium may influence the later growth and proliferation of follicles. Selenium may also impact positively the embryo development and survival.
Thanks to different benefits of Lynside Forte Se+ and Quatrefolic® are considered as a powerful combo for fertility. Indeed, a blend of these product support both men and women fertility. A supplement formulated with these two ingredients is suitable for men and women. One pill to support couple fertility.