The solution to diarrhea duration and dehydration
Millions of children worldwide suffer from diarrhea every year and are at risk of dehydration.
Oral rehydration is central in the World Health Organization’s guidelines on the management of acute diarrhea in children. Nevertheless, oral rehydration has no effect on the duration of diarrhea, but several natural and safe options may help limit the burden of acute diarrhea in children and adults.
Consistent evidence has shown the probiotic yeast strain Saccharomyces boulardii CNCM-I3799 may restore the microbiota balance in the gut. The strain is also one of the most documented nutritional interventions in reducing diarrhea duration in adults and children.
Classified as a subspecies of Saccharomyces cerevisiae, Saccharomyces boulardii CNCM-I3799 is specific strain of probiotic yeast, which differs considerably from many probiotic bacteria strains. Strain identifications is important as benefits may vary significantly between strains. It may help restore the balance of the microbiota and support the gut microbiota after disruption, though it doesn’t permanently colonize the human gut.
The new issue of our Science UP is dedicated to assessing the safety and efficacy of Saccharomyces boulardii CNCM-I3799, Gnosis’s probiotic yeast strain. This is relevant for the management of acute diarrhea in children, as well as during or after antibiotics, when symptoms may appear due to disrupt of the gut microbiota. Further, its use helps reduce antibiotic-associated diarrhea incidence, and it has been studied to support management of traveler’s diarrhea.
- Demonstrates the beneficial effect of S. boulardii CNCM I-3799 supplementation in reducing the duration and severity of diarrhea in infants and children.
- Confirms its consistency with the scientific literature on S. boulardii and its ability to survive harsh gut conditions.
S. boulardii was first identified in 1923 by Henri Boulard.
Deep dive into probiotic yeast
What is Saccharomyces boulardii I-3799 and what makes it different? It’s a probiotic yeast that helps at the intestinal level by supporting the intestinal barrier function and reducing permeability. It can also inhibit the adhesion of pathogens to the intestinal lining and helps strengthen the immune response by stimulating IgA, and its use has been explored in conditions like irritable bowel syndrome and inflammatory bowel disease.
