The decreased methylation and the low availability of S-adenosylmethionine (SAMe) that occurs in brain aging are closely linked with alteration of brain and cognitive functions and may involve nerve cell deterioration.
Age-associated neurological impairment can have a variety of forms including memory loss, senility, and dementia.
Supplementation of SAMe may improve mood and cognitive measures, support brain and neuronal health and boost the levels of antioxidants produced like glutathione (GSH).