Brain-Quantum Tablets – A Synergic Trio for Healthy Mood & Brain

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Brain-Quantum Tablet is an exclusive formula with Gnosis’ patented blockbuster ingredients – Adonat® Premium SAMe and Quatrefolic® – as well as vitamin B12, that work synergistically to nurture, sustain, and protect brain functionality while helping balance mood.

Gnosis’s standout BQ is delivered via proprietary tablet technology with enteric coating for optimized stability and improved absorption. 

According to Euromonitor International, mental health supplements have emerged from the COVID-19 era as the fastest-growing benefit within the global dietary supplements market. Growth of these supplements has been led by the US market, with category growth reaching 62% in 2022, a 27% CAGR from 2017(1). Although the social stigma has diminished, allowing quicker diagnosis of these problems, many individuals manifest mild impairment and often prefer natural alternative therapies to rebalance over pharmaceuticals. 

With 500 million people worldwide affected by mood disorders, and many suffering from nervousness, anxiety, and stress at least once in their lives, the problem applies not only to adults but also, increasingly often, to children and adolescents. Moreover, the COVID-19 pandemic has increased levels of distress, with mood impairment and anxiety symptoms in the general population(2). 

Growing Preference for Natural Alternatives

Social stigma and discrimination can worsen mental health problems and stop a person from getting the help they need.  Fortunately, after the pandemic, people have raised their sensitivity to these problems, sharing their experiences and discussing novel approaches to deal with them.  

Many individuals manifest mild impairment and, before receiving a medical diagnosis, they prefer to change their habits and help themselves by targeting nutrient imbalances through dietary modification, trying to rebalance their biological systems, with vitamins and bioactive ingredients. Moreover, despite advances in psychopharmacological treatment, many people are dissatisfied with conventional therapy, seeking other options without potential side effects.

How Brain-Quantum Tablets Can Help? (3,4)

In this scenario, the Brain Quantum Tablets can provide overall mental and brain well-being through Adonat® Premium SAMe, Quatrefolic® active folate, and Vitamin B12. Indeed, an intimate relationship exists between the metabolism of folate, vitamin B12, and SAMe. Deficiencies of these substances are associated with compromised mood, mild cognitive impairment, and brain discomfort, with reduced response to pharmacological treatment, greater likelihood of recurrence, and longer depressive episodes. 

Since vitamin B12 and folate levels decrease with aging, supplementation through a well-designed supplement can synergistically help neurobiological processes, ensure proper neurological and psychological function, and help reduce fatigue and exhaustion.  Moreover, SAMe is essential as the most crucial methylator agent in the body and serves primarily to methylate various acceptors, including nucleic acids (DNA and RNA), proteins, phospholipids, and biological amines It supports the production and recycling of our body’s signaling molecules, such as hormones and neurotransmitters.

Adonat®, Quatrefolic®, and Vitamin B12 in the One-Carbon Metabolism (3,4)

SAMe, 5-MTHF, and vitamin B12 work together in the one-carbon metabolism, a network of interrelated biochemical reactions that involves transferring one-carbon methyl groups from one compound to another. ​ 

Indeed, Vit B12 and folate are essential for the remethylation of homocysteine to methionine and the subsequent formation of SAMe, which is involved in normal brain functions. Interference with this process may result in the low SAMe availability and accumulation of serum total homocysteine, a recognized risk factor for cognitive impairment and dementia. 

The daily amount of SAMe that is required depends on the availability of the methionine produced by de novo synthesis (involving 5-MTHF and vit B12) and the methionine obtained from the diet, mainly from the breakdown of proteins.  

Brain-Quantum ready formula in tablets offers a comprehensive approach to optimal brain health, providing a union of three molecules able to cross the blood-brain barrier, making them immediately available for the brain: the most potent methylator (SAMe), the active form of folate (5-MTHF), and the easy-to-absorb methylcobalamin (vit B12), to support methylation and neurotransmitter synthesis for a healthy mood and good cognitive function and processing.


  1. Exploring the Booming Market for Mental Health Supplements –
  2. Risk Factors for Mental Illness | NCD Alliance 
  3. Cicero AF, Minervino A. Combined action of SAMe, Folate, and Vitamin B12 in the treatment of mood disorders: a review. Eur Rev Med Pharmacol Sci. 2022;26(7):2443-2459. doi:10.26355/eurrev_202204_28479 
  4. Bottiglieri T. Folate, vitamin B₁₂, and S-adenosylmethionine. Psychiatr Clin North Am. 2013;36(1):1-13. doi:10.1016/j.psc.2012.12.001

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The information provided here is, to the best of our knowledge, true and accurate. However, our products must only be used in compliance with local laws and regulations. We cannot guarantee the freedom of use for every intended application or country. These statements may not have been evaluated by your local Food and Drug Administration. Our products are not intended to diagnose, treat, cure, or prevent any disease. A healthy, balanced and diversified diet should fulfill all nutritional needs.