Phosphocomplex® is a synergistic, highly bioavailable complex of Silybin and Phosphatidylcholine, supporting liver health.

Silybin is the most abundant and potent constituent of silymarin, the most active ingredient of milk thistle plant (Silybum marianum) that has been extensively studied for its benefits in liver health. Unfortunately, Silybin has traditionally had poor intestinal absorption and a low bioavailability.

Phosphocomplex® improves Silybum’s capacity to reach circulation, resulting in enhanced bioavailability. Through its antioxidant and anti-inflammatory effects, the Silybin contained in Phosphocomplex® has the capacity to protect and normalize liver functions, also promoting the production of glutathione.

  • Product category
  • Active ingredients
  • Market segments
    • Digestion & Gut
  • Health benefits
    • Liver Health iconLiver
  • Allergens and
  • Gluten-free
  • Lactose-free
  • Non GMO

Phosphocomplex®: easy handling, simple storage, and consistent standards

Phosphocomplex® silybin by high-performance liquid chromatography (HPLC), making it suitable for different formulations such as tablets, capsules, and topical dosage formats.

Healthy liver function through four mechanisms of action

Phosphocomplex® is a rounded solution than offers an overall liver health support, from liver and cells protection to detoxication effects.

Better silymarin bioavailability

The phospholipid complexation of Silybin occurs with phospatidylcholine, which is an important emulsifier in the gastrointestinal tract and improves the capacity of the Silybin to cross lipid-rich bio-membranes and reach circulation, resulting in enhanced bioavailability.

Synergistic effect

Phosphocomplex® offers a synergistic effect of the phospholipid phosphatidylcholine as hepatoprotector.

Suitable for various formulations

Phosphocomplex® is suitable for different formulations such as tablets, capsules, and sachets, with a daily recommended dosage of 80 – 160 mg/day. It is also easy to handle and store.


Phosphocomplex® and Phosphocomplex®-containing products must not be used in women who are pregnant, attempting to become pregnant, or breastfeeding. Lesaffre disclaims all liability in respect of such information

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Frequently asked questions

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