Adonat® Portfolio
Adonat® Premium SAMe is a top-quality brand of S-Adenosyl-L-methionine (SAMe or SAM-e) derived through fermentation. SAMe is an important naturally occurring molecule with a critical role in one-carbon metabolism, a complex biochemical pathway that plays a critical role in DNA stability and key cellular components synthesis.
SAMe acts as a methylator agent, meaning that it is directly involved in key methylation processes involved in more than 100 biochemical pathways in the body, leading to many potential health benefits. These features make Adonat® Premium SAMe a compelling choice for individuals seeking a natural-based, safe, and effective supplement to support their health and wellbeing.

Embracing new quality-of-life standards with Adonat® Premium SAMe
The standout brand, Adonat® Premium SAMe, is the only branded SAMe on the market, backed by unmatched quality standards and flexible dosage forms. Formulating with Adonat® Premium SAMe provides supplement users with cutting-edge end-benefits, including proven effects on mood, cognitive, liver, and joint health.
Adonat® Premium SAMe supplementation works as a daily companion ally, supporting health span and longevity in adulthood. SAMe is endogenously produced and, when supplemented, is a comprehensive solution for brain health and liver detoxification and a key part of maintaining joint health.
Adonat® products
Our portfolio of patented stabilized forms, including our high-quality SAMe bulk powder, ensures the distinctive features of S-Adenosyl-L-methionine (SAMe) are preserved, providing unique and flexible ingredient solutions for specific market needs.
Comprehensive daily support for all ages
Adonat® Premium SAMe promotes healthy aging by rebalancing methylation patterns and regulating gene expression. Counteracting biological imbalances with daily supplementation of Adonat® Premium SAMe may help promote longevity, support health span, and protect against age-related diseases over time.


Healthy brain, mood and cognition
Adonat® Premium SAMe is a comprehensive solution for brain health. It supports emotional well-being, mood balance, cognitive function, and nootropic performance by working in key neurotransmission, neuroprotection, and neuroplasticity areas.
Revitalizing joint mobility and functions
Improve joint health with Adonat® Premium SAMe. This dietary supplement has been shown to help reduce inflammation, enhance joint health, and support pain relief in unique ways, making it an essential component for maintaining joint functions and countering compromised conditions.


Wall liver protection and detoxification
Support liver health and detoxification with Adonat® Premium SAMe. This dietary supplement enhances hepatic functions and helps counteract liver dysfunctions, promoting overall well-being. SAMe is primarily produced in the liver and can be supplemented for added support.
Mood & Cognitive
No matter how healthy our bodies are, our brain is what enables us to truly thrive!
Our brain controls our mood and behavior, and it drives us to learn, explore, remember, and create.
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