Adonat® Tablets

At Gnosis by Lesaffre, we offer an exclusive wide range of Adonat® Tablets available in two different proprietary coatings, enteric-coating and essential-coating, to fully meet the needs of our customers and the market, available in 200 and 400 mg dosages.

S-Adenosyl-L-methionine (SAMe or SAM-e) is a powerful endogenously produced molecule that supports whole human health, targeting mood, cognition, health span, longevity,  liver detoxification, and joint health.

Adonat® Tablets are formulated with the highest-quality SAMe available on the market - according to a comparative analysis on SAMe ingredients carried out – applying proprietary expertise and know-how.

Our Adonat® Tablets deliver reliable experiences for both manufacturers and consumers.

  • Product category
  • Active ingredients
  • Market segments
    • Mood & Cognitive
    • Mobility & Joint
    • Digestion & Gut
    • Wellness & Immune
  • Health benefits
    • Mood Health iconMood
    • Cognition iconCognition
    • Stress & Anxiety iconStress & Anxiety
    • attention-concentrationAttention and Concentration
    • Longevity
    • Joint Health iconJoint
    • Liver Health iconLiver
    • General-Wellbeing iconGeneral Wellbeing
  • Allergens and
  • Gluten-free
  • Lactose-free
  • Non GMO
  • Solvent FreeSolvent Free
  • Vegetarian-vegan iconVegetarian and Vegan

Proprietary tablet coating technology

Adonat® enteric-coated and enteric-coated tablets are innovative SAMe tablet formulations with different features. The enteric-coated tablet is a conventional dosage form and the first to gain success in the nutritional market, extensively studied for pharmaceutical and nutraceutical applications. The essential coated tablet is a new “free-form” formulation, using consumer-friendly excipients that offer value-added benefits while preserving the SAMe ingredient’s protective properties.

Exclusive BQ (Brain Quantum) tablets

Brain Quantum Tablets are a unique Adonat®-based SAMe tablet trio that synergistically supports methylation and neurotransmitter synthesis, ensuring healthy mood, cognitive functions, and processing. This trio includes the blockbuster folate Quatrefolic® and easy-to-absorb methylcobalamin (vit B12). Learn More.


Tableting expertise for turnkey solutions

Looking for an expert partner to help with challenging formulation projects involving SAMe tablet creation? Look no further. Our team at Adonat® specializes in providing turnkey solutions and working collaboratively with our customers to co-create tailor-made and innovative combinations with SAMe in tablet form.



Brain-Quantum ready formula in tablets offers a comprehensive approach to optimal brain health, with a synergy among three molecules able to cross the blood-brain barrier and to be immediately available on the brain.

Frequently asked questions

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