Adonat® Pure Ingredient

- Product category
Active ingredients
- Market segments
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Mood & Cognitive
Mobility & Joint
Digestion & Gut
Wellness & Immune
- Health benefits
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Mood
Cognition
Stress & Anxiety
Attention and Concentration
Longevity
Joint
Liver
General Wellbeing
- Allergens and
certificates Gluten-free
Halal
Kosher
Lactose-free
Non GMO
Solvent Free
Vegetarian and Vegan
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Gnosis by Lesaffre: The first to market in SAMe
Gnosis by Lesaffre was the first company to introduce and commercialize SAMe in the nutraceuticals worldwide market. Today, its cGMP-approved manufacturing plant in Switzerland guarantees the highest quality standards.
Our SAMe brand Adonat® Premium SAMe is produced by a biotransformation process of saccharomyces cerevisiae yeast cultures and is purified without the use of solvents.
Watch the video and discover 5 new features about Adonat® Premium SAMe (S-Adenosyl-L-methionine).
Science continues to advance on methylation
Methylation occurs approximately one billion times per second in the body and influences nearly every essential process, emerging as predictive biomarkers for early disease risk and life expectancy. Incorporating Adonat®
Premium SAMe into supplements can deliver powerful health benefits while positioning products as cutting-edge and forward-thinking.


Gnosis by Lesaffre: the first to market in SAMe
Gnosis by Lesaffre was a pioneering company in introducing SAMe in the nutraceuticals worldwide market. Our Adonat®
Premium SAMe brand is produced by a biotransformation process of Saccharomyces cerevisiae yeast cultures, in a cGMP-approved manufacturing plant in Switzerland, with a strict quality management system that guarantees the highest quality standards.
A best-in-class manufacturing process and supply chain
Gnosis is the top global producer of pharmaceutical-grade SAMe (AATC Code “Alimentary Tract and Metabolism: A16AA02”) in their approved pharmaceutical plant.
Our highly trained staff ensures strict adherence to cGMP regulations for both pharmaceutical and nutraceutical production. The entire supply chain is consistently optimized and closely controlled, with all manufacturing steps protecting and respecting the active ingredient.

Mood & Cognitive
No matter how healthy our bodies are, our brain is what enables us to truly thrive!
Our brain controls our mood and behavior, and it drives us to learn, explore, remember, and create.
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Latest news & events

- Adonat®
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- Feb 17, 2025
Adonat® Shines in Vitamin Retailer’s Top 10 Stories of 2024
Vitamin Retailer's annual roundup of the top stories of 2024 features a standout article...

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- Jan 13, 2025
Adonat® Premium SAMe for Menopausal Women’s Well-Being
The S-adenosyl-L-methionine (SAMe) can be a versatile molecule in alleviating various symptoms associated with...

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Gnosis by Lesaffre Showcases at Denk Ingredient’s Annual Symposium in Munich
Gnosis by Lesaffre was a key presenter for Denk Ingredients' annual symposium in Munich,...