
Research has shown that up to 20% of bone loss can occur during menopause, making proper health management essential. Dietary choices, regular exercise, and medications can help prevent further bone loss and decrease the risk of fractures.
However, osteoporosis is often known as ‘a silent disease’ and is likely to be determined by the first bone break or a decrease in bone density.
Quatrefolic® can potentially reduce the risk of osteoporosis by normalising homocysteine levels, an amino acid that helps support bone structure.
In a recent study, women aged 60 years and older who consumed an optimal amount of folate were found to have a lower chance of developing osteoporosis. Osteoporosis is a common issue in older women, particularly after menopause, which can lead to an increased risk of fractures and other health concerns.
The research highlights the importance of prioritizing optimal folate intake through a nutrient-rich diet and targeted supplementation. By reducing the risk of osteoporosis and other age-related health issues, older women can enjoy a higher quality of life and maintain their independence.
Active form of folate: 5-MTHF
Supplementation with active folate 5-MTHF, such as Quatrefolic®, bypasses the entire folate metabolisation process, and 5-MTHF is directly absorbed to exert its biological activity and advantages.
A study published in The American Journal of Clinical Nutrition suggests highlighting the relationship between folate and osteoporosis in older women. The research, involving a cohort of older women, found that those with higher folate levels had a reduced risk of developing osteoporosis compared to those with lower levels.
This effect is believed to be linked to folate’s ability to reduce levels of homocysteine, an amino acid that, at elevated levels, is associated with bone density loss and an increased risk of fractures.
Latest News

- News
- Quatrefolic®
- Wellness & Immune
- Jun 12, 2025
Webinar Rethinking Women’s Health 24 June 2025
Women's health is complex, constantly evolving, and a broader perspective is long overdue, one...

- News
- Quatrefolic®
- Wellness & Immune
- Jun 09, 2025
Gnosis by Lesaffre Highlights Quatrefolic® at New Nutrition Forum in Hangzhou, China
Gnosis by Lesaffre was proud to serve as the Title Sponsor of the New...

- Corporate
- Digestion & Gut
- News
- Jun 06, 2025
Biotic Live: A Successful First Edition Exploring the Power of Probiotic Yeasts
Gnosis by Lesaffre recently hosted the first edition of Biotic Live, a unique event...