ibSium®
Intestinal problems are not only uncomfortable for people to endure, but they also elevate stress levels. Enter ibSium® (Saccharomyces cerevisiae CNCM I-3856), a probiotic yeast clinically proven to support overall intestinal comfort.
The gut is well-known today as the center of our overall health. From helping to manage abdominal discomfort, bloating, recurrent transit disorders, and pain associated with a disorder of gut-brain interaction, ibSium® can improve everyday digestive well-being and quality of life.
With more than 96% of consumers reporting a significant improvement in gut comfort, ibSium® is your customers’ daily ally for complete intestinal support.
Market Segments
- Digestion & Gut
Health Benefits
- Diarrhea Management
- Digestive Comfort
- Microbiome Balance
Allergens and Certificates
- Gluten-free
- Halal
- Kosher
- Lactose-free
- Vegetarian and Vegan
ibSium®: A Patented and Unique Yeast-Based Probiotic
IbSium® is the brand name of our unique probiotic yeast Saccharomyces cerevisiae CNCM I-3856 , an exclusive strain selected by our experts among our proprietary collection of strains for its superior capacity to help alleviate occasional intestinal disorders.
S. cerevisiae CNCM I-3856 is protected by an international patent. It survives through the gastrointestinal tract and requires no refrigeration.
A Proprietary Strain Backed by an International Patent
ibSium®’s patented strain of Saccharomyces cerevisiae survives through the gastrointestinal tract and requires no refrigeration.

Supported Strong Science
S. cerevisiae CNCM I-3856 has more than 15 years of clinical research, including:
4 clinical studies (including one independent) on more than 670 volunteers
1 meta-analysis confirming our robust science
The guarantee of recognized and independent experts in digestive conditions
A Unique Expertise in Yeast Production
Thanks to the Lesaffre Group’s 170 years of yeast fermentation and production expertise, S. cerevisiae CNCM I-3856 is obtained through fine-tuned production and drying processes. Thus, we can offer a powerful probiotic with the following benefits:
- Long shelf life (up to 36 months)
- A superior stability in various packaging for optimal use in dietary supplements

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