
Thanks to its bioavailability, Quatrefolic® has become the reference for folate dietary supplements. It guarantees the right dosage of biologically active folate that can immediately supports the reproductive stage, homocysteine metabolism, cardiovascular health, mood & brain functioning.
The human body cannot produce folate by itself, therefore must necessarily be introduced by the diet. In vivo, folic acid and food folates must be converted to 5-MTHF, through a multi-steps process where the enzyme methylenetetrahydrofolate reductase (MTHFR) owns a key role.
Decreased activities of MTHFR enzyme are present in some individuals, due to their unique genetic patterns and expression: they have polymorphic forms of this enzyme, which are associated with reduced plasma levels of the biologically active 5-MTHF folate.
The benefits of Quatrefolic®, the right choice of folate
Quatrefolic® does not need any specific metabolism to guarantee all the benefits. The 5-MTHFR provides all the nutritional benefits directly, without “genetic” impacts on the bioavailable blood folate. Cellular regeneration is an ongoing process in the body, from our skin layers, nails, and hair growth, which requires protein and DNA production to more complex body functions.
Quatrefolic® plays a pivotal role in tissue growth, one carbon metabolism and cell function. It works with vitamin B12, vitamin B6, and vitamin C to break down and create new proteins.
Benefit targets are huge from healthy pregnancy, fertility, well function of the immune system, cardiovascular protection, and balanced homocysteine level in blood.
DISCOVER ALL OUR LATEST NEWS

Supplementation with Menaquinone-7 (as MenaQ7®) Slows the Progression of Coronary Artery Calcification
The first results from the VitaK-CAC Trial, “Menaquinone-7 Slows Down Progression of Coronary Artery Calcification: A Randomized, Placebo-Controlled Trial,” were presented at the 34th European Meeting on Hypertension and Cardiovascular Protection, organized by the European Society of Hypertension (ESH), held in Milan in May 23–26, 2025.

Natural Probiotic Yeast Support on World Digestive Health Day
Each year on May 29, World Digestive Health Day raises global awareness about the importance of a healthy digestive system. This day serves not only as a reminder of digestive well-being, but also as a call to action—to understand better and support the millions living with gastrointestinal disorders.

Infodemiology Offers a Fresh Lens on Nutritional Yeast
Haven’t you ever wondered what consumers think about yeast? Infodemiology, an innovative social media listening approach, provides insights into how consumers perceive nutritional yeast.