As the planet and its people advances with science, Quatrefolic® works alongside you to invigorate lives and improve living, by providing the right folate supplementation at all life stages.
At Gnosis by Lesaffre, it is our responsibility to provide ethical products for the people. By creating Quatrefolic®, the 4th generation innovative folate, we aim to improve the folate status, especially in pregnant women to protect their embryos and fetuses.
Quatrefolic® and its numerous clinical studies, is the glucosamine salt of (6S)-5-methyltetrahydrofolate (5-MTHF) and is structurally identical to the reduced and active form of folate found in our bodies.
As we aim to give meaning to life through science, we invite you to watch our new video which is now on Quatrefolic® YouTube Channel.
Latest news & videos

- News
- Quatrefolic®
- Wellness & Immune
- Jun 12, 2025
Webinar Rethinking Women’s Health 24 June 2025
Women's health is complex, constantly evolving, and a broader perspective is long overdue, one...

- News
- Quatrefolic®
- Wellness & Immune
- Jun 09, 2025
Gnosis by Lesaffre Highlights Quatrefolic® at New Nutrition Forum in Hangzhou, China
Gnosis by Lesaffre was proud to serve as the Title Sponsor of the New...

- Corporate
- Digestion & Gut
- News
- Jun 06, 2025
Biotic Live: A Successful First Edition Exploring the Power of Probiotic Yeasts
Gnosis by Lesaffre recently hosted the first edition of Biotic Live, a unique event...