Adonat® Pure Ingredient

Expertise and know-how are key aspects of Adonat® Premium SAMe bulk, to guarantee the highest quality SAMe available on the market, co-creating value for customers and supplements that meet market expectations. SAMe is a powerful endogenously produced molecule that, when supplemented, provides numerous benefits for whole human health, including Mood & Cognitive health, Health Span & Longevity, and Joint and Liver health.
A comparative analysis confirms its superior quality over other SAMe ingredients, providing a reliable experience for manufacturers and consumers alike.
  • Product category
  • Active ingredients
  • Market segments
    • Mood & Cognitive
    • Mobility & Joint
    • Digestion & Gut
    • Wellness & Immune
  • Health benefits
    • Mood Health iconMood
    • Cognition iconCognition
    • Stress & Anxiety iconStress & Anxiety
    • attention-concentrationAttention and Concentration
    • Longevity
    • Joint Health iconJoint
    • Liver Health iconLiver
    • General-Wellbeing iconGeneral Wellbeing
  • Allergens and
  • Gluten-free
  • Halal
  • Kosher
  • Lactose-free
  • Non GMO
  • Solvent FreeSolvent Free
  • Vegetarian-vegan iconVegetarian and Vegan

Gnosis by Lesaffre: The first to market in SAMe

Gnosis by Lesaffre was the first company to introduce and commercialize SAMe in the nutraceuticals worldwide market. Today, its cGMP-approved manufacturing plant in Switzerland guarantees the highest quality standards.

Our SAMe brand Adonat®  Premium SAMe is produced by a biotransformation process of saccharomyces cerevisiae yeast cultures and is purified without the use of solvents.

Watch the video and discover 5 new features about Adonat® Premium SAMe (S-Adenosyl-L-methionine).

Science continues to advance on methylation

Methylation occurs approximately one billion times per second in the body and influences nearly every essential process, emerging as predictive biomarkers for early disease risk and life expectancy. Incorporating Adonat®
Premium SAMe into supplements can deliver powerful health benefits while positioning products as cutting-edge and forward-thinking.

Gnosis by Lesaffre: the first to market in SAMe

Gnosis by Lesaffre was a pioneering company in introducing SAMe in the nutraceuticals worldwide market. Our Adonat®
Premium SAMe brand is produced by a biotransformation process of Saccharomyces cerevisiae yeast cultures, in a cGMP-approved manufacturing plant in Switzerland, with a strict quality management system that guarantees the highest quality standards.

A best-in-class manufacturing process and supply chain

Gnosis is the top global producer of pharmaceutical-grade SAMe (AATC Code “Alimentary Tract and Metabolism: A16AA02”) in their approved pharmaceutical plant.
Our highly trained staff ensures strict adherence to cGMP regulations for both pharmaceutical and nutraceutical production. The entire supply chain is consistently optimized and closely controlled, with all manufacturing steps protecting and respecting the active ingredient.


Mood & Cognitive

No matter how healthy our bodies are, our brain is what enables us to truly thrive!  

Our brain controls our mood and behavior, and it drives us to learn, explore, remember, and create.

Frequently asked questions

What's the best thing about Switzerland?
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How do you make holy water?
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