ibSium® (Saccharomyces cerevisiae CNCM I-3856) is probiotic yeast clinically proven to support overall intestinal comfort.

As the gut is today well-known to be the center of our overall health, from helping to manage abdominal discomfort, bloating or recurrent transit disorders, and Irritable Bowel Syndrom (IBS) symptoms, ibSium® can improve everyday digestive comfort and quality of life.

With more than 96% of consumers reporting a significant improvement of gut comfort, ibSium® is your customers’ daily ally for complete intestinal support.

  • Product category
  • Biotics
  • Market segments
    • Digestion & Gut
  • Health benefits
    • diarrhea management iconDiarrhea Management
    • digestive comfort iconDigestive Comfort
    • Microbiome balance iconMicrobiome Balance
  • Allergens and
  • Gluten-free
  • Halal
  • Kosher
  • Lactose-free
  • Non GMO
  • Vegetarian-vegan iconVegetarian and Vegan

ibSium®: patented and unique yeast-based probiotic

ibSium® is the brand name of our unique probiotic yeast Saccharomyces cerevisiae CNCM I-3856, an exclusive strain selected by our experts among our proprietary collection of strains for its superior capacity to help alleviate occasional intestinal disorders.

S. cerevisiae CNCM I-3856 is protected by an international patent.

A proprietary strain backed by an international patent

ibSium’s patented strain of Saccharomyces cerevisiae survives through the gastrointestinal tract and requires no refrigeration.


Supported by strong science

Saccharomyces cerevisiae CNCM I-3856 benefits from:

• Three clinical studies (including one independent) on more than 670 volunteers
• The guarantee of recognized and independent experts in digestive diseases
• A meta-analysis confirming our robust science and strengthening our conclusions

Consumer-approved, fast-acting support

A study conducted on more than 1,160 volunteers reported more than 96% satisfaction of gut comfort improvement with IbSium®.
Three out of four participants experienced positive effects on their digestive comfort within the 15 first days of consumption.

A unique expertise in yeast production

Thanks to the Lesaffre Group’s 170 years expertise in yeast fermentation and production, S. cerevisiae CNCM I-3856 is obtained through fine-tuned production and drying processes. Thus, we can offer a powerful probiotic with the following benefits:

• A long shelf life (up to 36 months)

• A superior stability in various packaging for optimal use in dietary supplements

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Frequently asked questions

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