Active Folate and MTHFR Polymorphism
Folate, also known as vitamin B9, is an essential nutrient that plays a crucial role in numerous bodily functions, from cell growth and development to DNA synthesis. However, for individuals with genetic variations in the methylenetetrahydrofolate reductase (MTHFR) enzyme, the benefits of folate can be significantly impaired.
5,10-methylenetetrahydrofolate reductase (MTHFR) is the key enzyme in the biosynthesis of an active folate form.
Genetic polymorphisms in the MTHFR gene, such as the C677T and A1298C variants, can reduce the enzyme’s activity, leading to the accumulation of homocysteine in the body.
Elevated homocysteine levels have been linked to a range of health concerns, including cardiovascular disease, neurological disorders, and pregnancy complications.
This is where the advantages of active folate, such as Quatrefolic®, come into play.
Watch the video and discover how Quatrefolic®/ can bypass the MTHFR conversion step and deliver a «finished» folate the body can immediately use without any metabolization.
Latest news & videos
- MenaQ7®
- Mobility & Joint
- News
- Jun 02, 2025
Supplementation with Menaquinone-7 (as MenaQ7®) Slows the Progression of Coronary Artery Calcification
The first results from the VitaK-CAC Trial, “Menaquinone-7 Slows Down Progression of Coronary Artery...
- Digestion & Gut
- ibSium®
- News
- May 29, 2025
Natural Probiotic Yeast Support on World Digestive Health Day
Each year on May 29, World Digestive Health Day raises global awareness about the...
- Lynside® Nutritional Yeasts
- News
- Wellness & Immune
- May 27, 2025
Infodemiology Offers a Fresh Lens on Nutritional Yeast
Haven’t you ever wondered what consumers think about yeast? Infodemiology, an innovative social media...
