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New Quatrefolic® Educational Videos: MTHFR Polymorphism

Published on
September 20, 2024
Extrafolate crystal

    Active Folate And MTHFR Polymorphism

    Approximately half of the global population may carry some form of MTHFR mutation.  MTHFR deficiency may predispose individuals to hyperhomocysteinemia (high blood homocysteine levels) in a dynamic interaction between genetics and nutrition.  Quatrefolic®, the active form of folate, is recommended to support well-being and reduce health risks in these individuals.

    Folate, also known as vitamin B9, is an essential nutrient that plays a crucial role in numerous bodily functions, from cell growth and development to DNA synthesis. However, for individuals with genetic variations in the methylenetetrahydrofolate reductase (MTHFR) enzyme, the benefits of folate can be significantly impaired. 

     

    5,10-methylenetetrahydrofolate reductase (MTHFR) is the key enzyme in the biosynthesis of an active folate form. 

     

    Genetic polymorphisms in the MTHFR gene, such as the C677T and A1298C variants, can reduce the enzyme’s activity, leading to the accumulation of homocysteine in the body. 

     

    Elevated homocysteine levels have been linked to a range of health concerns, including cardiovascular disease, neurological disorders, and pregnancy complications.

     

    This is where the advantages of active folate, such as Quatrefolic®, come into play. 

     

    Discover how Quatrefolic® can bypass the MTHFR conversion step and deliver a «finished» folate the body can immediately use without any metabolization.

     

    New Quatrefolic® Educational Videos

    Deep Dive Into Folate

    Folate, also known as vitamin B9 or folic acid, is a water-soluble essential nutrient that plays a crucial role in many physiological processes in the body, such as healthy cell growth, DNA synthesis, and red blood cell formation.